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Venetia Zachariou, PhD
img_Venetia Zachariou
ADJUNCT PROFESSOR | Neuroscience
212-659-6882
email
Research Topics
Addiction, Behavioral Health, Brain, Depression, Epigenetics, Gene Therapy, Knockout Mice, Membrane Proteins/Channels, Molecular Biology, Neurobiology, Neuroscience, Obesity, Opioid/Cannabinoid Receptors, Pain, Pharmacology, Protein Complexes, Signal Transduction, Spinal Cord, Synaptic Plasticity, Systems Neuroscience, Tolerance, Transcription Factors, Transgenic Mice
Multi-Disciplinary Training Area
Disease Mechanisms and Therapeutics (DMT), Neuroscience [NEU]
Research Areas:
  • The function of signal transduction complexes in the striatum in drug addiction
  • Regulation of G protein signaling in chronic stress and antidepressant treatment
  • Novel intracellular targets for the treatment of chronic pain
  • Epigenetic adaptations in neuropathic and inflammatory pain
  • The role of the brain reward center in chronic pain and its treatment
90
Publications

Selected Publications

Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury. Kerri D. Pryce, Randal A. Serafini, Aarthi Ramakrishnan, Andrew Nicolais, Ilinca M. Giosan, Claire Polizu, Angélica Torres-Berrío, Sreeya Vuppala, Hope Kronman, Anne Ruiz, Sevasti Gaspari, Catherine J. Peña, Farhana Sakloth, Vasiliki Mitsi, John van Duzer, Ralph Mazitschek, Matthew Jarpe, Li Shen, Eric J. Nestler, Venetia Zachariou. Nature Neuroscience

Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration. Alon Lai, Denise Iliff, Kashaf Zaheer, Dalin Wang, Jennifer Gansau, Damien M. Laudier, Venetia Zachariou, James C. Iatridis. International Journal of Molecular Sciences

A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward. Farhana Sakloth, Omar B. Sanchez-Reyes, Anne Ruiz, Andrew Nicolais, Randal A. Serafini, Kerri D. Pryce, Feodora Bertherat, Angélica Torres-Berrío, Ivone Gomes, Lakshmi A. Devi, Daniel Wacker, Venetia Zachariou. Molecular Pharmacology

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Icahn (East) Building Floor 10 Room 02 (Lab)

1425 Madison Ave

New York, NY 10029

212-659-6882

Icahn (East) Building Floor 10 Room 20B

1425 Madison Ave

New York, NY 10029

212-659-8612

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Zachariou is not currently required to report Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.