Steven G Coca, DO

img_Steven G Coca
PROFESSOR | Medicine, Nephrology
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Specialties
Internal Medicine, Nephrology
Dr. Coca is actively involved in clinical and translational research that focuses on using biomarkers to improve risk-stratification for outcomes in acute and chronic kidney disease. The development of prognostic and predictive biomarkers may aide future clinical trials, by serving as an enrichment strategy for enrollment, and may also serve as outcomes for early phase trials of novel interventions. He has leveraged existing cohorts with banked blood and urine samples, including the ACCORD, VA NEPHRON-D, CANVAS, and DAPA-CKD clinical trials, as well as the Mount Sinai BioMe Biobank and the UPenn Medicine Biobank to explore the prognostic, discriminative, and additional value of biomarkers in AKI and CKD. He has been an active investigator in several large NIH consortia, including the TRIBE-AKI, ASSESS-AKI, CKD Biocon, and Kidney Precision Medicine Project (KPMP). He plans to continue exploring these parameters in other large cohorts and then to design innovative trials employing biomarkers for facilitated enrollment and for better determination of efficacy of existing or new agents.

DO, University of New England College of Osteopathic Medicine

MS, Yale University Graduate School of Arts and Sciences

Residency, Internal Medicine, Yale University School of Medicine

Fellowship, Nephrology, Yale University School of Medicine

Certifications

American Board of Internal Medicine

2021

ASN

Midcareer Distinguished Researcher Award

2021

Top Reviewer Award

American Journal of Nephrology

2019

MSIP

“Deal of the Year Award” (for RenalytixAI; shared with Drs. Murphy and Nadkarni)

2018

Stanley L. Cohen Memorial Lecture & Award

Yale New Haven/Bridgeport Hospital Foundation

2017

Joseph R. Renda Memorial Award

Yale University School of Medicine

2013

Junior Physician Investigator Award

American Federation for Medical Research

2013

AFMR 2013 Junior Physician Investigator Award

American Federation for Medical Research

2008

ASN

ASP Junior Development Grant in Geriatric Nephrology

2008

T. Franklin Williams Scholar

2008

K23 Career Development Award

NIH/NIDDK

2008

NIH Loan Repayment Program

NIH

2007

Henry Christian Award

American Federation for Medical Research

2002

Intern of the Year

Yale Primary Care Internal Medicine Program

2007

Henry Christian Award

American Federation for Medical Research

2021

Midcareer Distinguished Researcher Award,

American Society of Nephrology

2020

Top 5 Reviewer of the Year

Journal of the American Society of Nephrology

2019

Top 5 Reviewer of the Year

Clinical Journal of the American Society of Nephrology

2019

MSIP “Deal of the Year Award”

(for RenalytixAI; shared with Drs. Murphy and Nadkarni)

2018

Top 5 Reviewer of the Year,

Journal of the American Society of Nephrology

2018

Top 5 Reviewer of the Year,

Clinical Journal of the American Society of Nephrology

2017

4D Technology Development Program Award

SINAInnovations

Publications

Selected Publications

Cost-effectiveness analysis of a prognostic risk assessment for early-stage 1-3b diabetic kidney disease patients in the United States. Jacie T. Cooper, John E. Schneider, Thomas Mclain, Steven Coca, Michael J. Donovan. Cost Effectiveness and Resource Allocation

Real-World Associations of KidneyIntelX Risk Stratification With Guideline-Directed Therapy, Kidney Outcomes, and Metabolic Trajectories in Early Diabetic Kidney Disease. David Lam, Barry I. Freedman, Joji Tokita, Fergus Fleming, Mayte Suarez-Farinas, Benjamin Bagwell, Julienne Kirk, Hazel Tapp, Lindsay Shade, Aida Vega, Stephanie Wang, Catherine Sinfield, Steven G. Coca, Girish N. Nadkarni, Michael J. Donovan. Diabetes, Obesity and Metabolism

Acute tubular injury versus acute interstitial nephritis in the kidney precision medicine project. Jennifer A. Schaub, Rajasree Menon, Ricardo Melo Ferreira, Elizabeth Kiernan, Insa M. Schmidt, Christine P. Limonte, Soumya Yennapureddy, Ying Hua Cheng, Leal Herlitz, Avi Z. Rosenberg, Joel M. Henderson, Kelly D. Smith, Jeffrey B. Hodgin, Edgar Otto, Gilbert W. Moeckel, Lloyd G. Cantley, Suman Setty, Ulysses Gj Balis, Dawit Demeke, Agnes B. Fogo, Andrew S. Bomback, Vivette D. D'Agati, Isaac E. Stillman, Jose R. Torrealba, Allen R. Hendricks, Erika Bracamonte, Vanessa Moreno, Pavan Bhatraju, Amy K. Mottl, Frank C. Brosius, Bijin Thajudeen, Steven G. Coca, Paul M. Palevsky, Parmjeet S. Randhawa, Raghavan Murugan, Laura Barisoni, Charles E. Alpers, Steven Menez, F. Perry Wilson, Dennis G. Moledina, Michael T. Eadon, Matthias Kretzler, Jonathan Himmelfarb, Chirag R. Parikh. JCI insight

View All Publications

New Insights into the Diagnosis and Treatment of AKI in Patients with ADHF

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Coca during 2025 and/or 2026. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Merck & Co., Inc.
  • Bayer Inc.

Founder/Co-Founder/Partner

  • Renalytix AI, Inc

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.