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Samuel E Gandy, MD, PhD
img_Samuel E Gandy
PROFESSOR | Neurology
PROFESSOR | Psychiatry
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Specialties
Neurology
Research Topics
Alzheimer's Disease, Biochemistry, Biomedical Sciences, Biophysics, Brain, Brain Imaging, Cell Biology, Cognitive Neurology, Cognitive Neuroscience, Drug Design and Discovery, Genetics, Genomics, Hippocampus, Hormones, IGF-1 Receptor, Immunology, Induced pluripotent stem cells, Inflammation, Interferon, Intracellular Transport, Lipid Signaling, Lysosomes/endosome, Macrophage, Mass Spectrometry, Memory, Metabolism, Microglia, Neuro-degeneration/protection, Neurobiology, Neurology, Neuronal Regeneration, Neuroscience, Neurotoxicology, Neurotransmitters, Personalized Medicine, Pharmacogenomics, Pharmacology, Phosphorylation, Positron Emission Tomography, Prefrontal Cortex, Proteases, Protein Complexes, Protein Degradation, Protein Folding, Protein Kinases, Protein Phosphatases, Protein Structure/Function, Protein Trafficking & Sorting, Proteomics, Psychiatry, Receptors, Regeneration, Stem Cells, Synapses, Synaptic Plasticity, Synaptogenesis, Systems Biology, T Cells, Trafficking, Viruses and Virology
Multi-Disciplinary Training Area
Genetics and Genomic Sciences [GGS], Neuroscience [NEU]

MD, scu

MD, PhD, Medical University of South Carolina

Internship, Internal Medicine, Columbia University Irving Medical Center

Residency, Neurology, New York Presbyterian Hospital-Weill Cornell

Certifications

American Board of Psychiatry and Neurology

2008

Arthur Cherkin Memorial Award in Geriatric Medicine

338
Publications

Selected Publications

Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer's Aβ oligomers. Sam Gandy. Trends in Molecular Medicine

Author Correction: The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis (Nature Reviews Cardiology, (2023), 20, 6, (418-428), 10.1038/s41569-022-00818-2). Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini, Philippe Pibarot, Giampaolo Merlini, Robert S. Rosenson, Surya V. Seshan, Edgar Argulian, Amir Ahmadi, Fang Zhou, Andre L. Moreira, Nancy Côté, Sotirios Tsimikas, Valentin Fuster, Sam Gandy, Robert O. Bonow, Olga Gursky, Jagat Narula. Nature Reviews Cardiology

Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease. Emilie L. Castranio, Philip Hasel, Jean Vianney Haure-Mirande, Angie V. Ramirez Jimenez, B. Wade Hamilton, Rachel D. Kim, Charles G. Glabe, Minghui Wang, Bin Zhang, Sam Gandy, Shane A. Liddelow, Michelle E. Ehrlich. Alzheimer's and Dementia

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EMPHASIZE PREVENTION: How much science do we need to act?
CSU Magazine: Dr. Sam Gandy
Dr. Sam Gandy - Alzhiemer's Part 2
Dr. Sam Gandy - Alzhiemer's Part 1
GE At Work 2014 - From NFL Players to Boxers Lessons from Brain Trauma in Sport - Prof Sam Gandy
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Annenberg Building Floor 14 Room 73

1468 Madison Ave

New York, NY 10029

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Gandy during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting:

  • Altpep
  • Cognition Therapeutics Inc. (CogRX)
  • Bell Legal Group

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.