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Robert M Samstein, MD, PhD
img_Robert M Samstein
ASSISTANT PROFESSOR | Radiation Oncology
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Specialties
Radiation Oncology
Research Topics
Anti-Tumor Therapy, Autoimmunity, Biomedical Sciences, Breast Cancer, Cancer, Cancer Genetics, Cellular Immunity, Clinical Genomics, DNA Recombination, DNA Repair, Genetics, Genomics, Immunology, Mucosal Immunology, Oncogenes, Personalized Medicine, Pharmacogenomics, T Cells, Translational Research, Tumor Suppressor Genes, Tumorigenesis
Multi-Disciplinary Training Area
Cancer Biology [CAB], Immunology [IMM]
Dr. Samstein’s research interests are focused on understanding the interaction between the patient’s immune system and cancer cells in the tumor, elucidating the role of the DNA damage repair and response pathway in altering the tumor’s ability to be recognized and attacked by the immune system. His laboratory will work to identify new strategies to harness the immune anti-tumor response and expand the therapeutic window of traditional immunotherapies.

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MD, Weill Medical College of Cornell University

MD, Weill Cornell Medical College

PhD, Weill Cornell / Sloan Kettering / Rockefeller Tri-I MD-PhD Program

Memorial Sloan Kettering Cancer Center

Internship, Transitional Year, Memorial Sloan-Kettering Cancer Center

Residency, Radiation Oncology, Memorial Sloan-Kettering Cancer Center

Certifications

Radiation Oncology

2020

Solomon Silver Award in Clinical Medicine

2020

American Association of Immunologists Pfizer-Showell Award

2019

Burrough Wellcome Career Award for Medical Scientists

2019

RSNA Roentgen Reseach Award

2018

AACR Translational Immunology Award

2017

American Board of Radiology Holman Research Pathway

47
Publications

Selected Publications

Radiotherapy and Immunotherapy in Lung Cancer. Kristin Hsieh, Daniel R. Dickstein, Juliana Runnels, Eric J. Lehrer, Kenneth Rosenzweig, Fred R. Hirsch, Robert M. Samstein. Biomedicines

MHCing the tumour’s dark genome. Miriam Saffern, Robert Samstein. Nature Reviews Immunology

Leveraging big data of immune checkpoint blockade response identifies novel potential targets. Y. Bareche, D. Kelly, F. Abbas-Aghababazadeh, M. Nakano, P. N. Esfahani, D. Tkachuk, H. Mohammad, R. Samstein, C. H. Lee, L. G.T. Morris, P. L. Bedard, B. Haibe-Kains, J. Stagg. Annals of Oncology

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Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Samstein during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Royalty Payments:

  • Personal Genome Diagnostics

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.