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Peter H Rudebeck, PhD
img_Peter H Rudebeck
ASSOCIATE PROFESSOR | Neuroscience
ASSOCIATE PROFESSOR | Psychiatry
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Research Topics
Behavior, Bioinformatics, Brain, Cerebral Cortex, Cognitive Neuroscience, Computational Neuroscience, Electrophysiology, Memory, Motor Neuron, Neural Networks, Neurophysiology, Neuroscience, Prefrontal Cortex, Systems Neuroscience
Multi-Disciplinary Training Area
Neuroscience [NEU]
Neurobiology of Emotion and Cognition

In our daily lives we often encounter both pleasurable and aversive situations, which heighten our emotional state and affect cognition. The ability to flexibly regulate our emotions in response to such events is essential for adapting to our environment and, ultimately, for our mental health. Many forms of mental illness involve dysfunction in the neural systems that regulate affective processing. The limbic system, which includes parts of the prefrontal cortex and medial temporal lobe, is critical for regulating emotions and plays an essential role in cognition. The main focus of the Rudebeck lab is to understand how the limbic system, specifically the amygdala and ventromedial prefrontal cortex, contribute to emotional regulation and decision-making. To do this, we use a combination of behavioral, autonomic, neurophysiological and lesion approaches in animal models.  


Visit Peter Rudebeck's Laboratory of Neurobiology of Emotion & Cognition for more information.

PhD, University of Oxford

2017

Career Development Award

Society for Neuroscience

2016

NIMH BRAINS Award

NIMH

2009

Julius Axelrod Memorial Fellowship

National Insitute of Mental Health

50
Publications

Selected Publications

Temporally specific patterns of neural activity in interconnected corticolimbic structures during reward anticipation. Megan E. Young, Camille Spencer-Salmon, Clayton Mosher, Sarita Tamang, Kanaka Rajan, Peter H. Rudebeck. Neuron

Single basolateral amygdala neurons in macaques exhibit distinct connectional motifs with frontal cortex. Zachary R. Zeisler, Liza London, William G. Janssen, J. Megan Fredericks, Catherine Elorette, Atsushi Fujimoto, Huiqing Zhan, Brian E. Russ, Roger L. Clem, Patrick R. Hof, Frederic M. Stoll, Peter H. Rudebeck. Neuron

Resting-State fMRI-Based Screening of Deschloroclozapine in Rhesus Macaques Predicts Dosage-Dependent Behavioral Effects. Atsushi Fujimoto, Catherine Elorette, J. Megan Fredericks, Satoka H. Fujimoto, Lazar Fleysher, Peter H. Rudebeck, Brian E. Russ. Journal of Neuroscience

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Hess CSM Building Floor 10 Room 203A

1470 Madison Ave

New York, NY 10029

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Dr. Rudebeck did not report having any of the following types of financial relationships with industry and other outside entities during 2023 and/or 2024: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.