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Matilde Inglese, MD, PhD

img_Matilde Inglese
ADJUNCT PROFESSOR | Neurology
ADJUNCT PROFESSOR | Neuroscience
ADJUNCT PROFESSOR | Diagnostic, Molecular and Interventional Radiology
212-824-9310
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Research Topics
Blood-Brain Barrier, Brain Imaging, Cerebellum, Cognitive Neurology, Diffusion Tensor Imaging, Microglia, Mitochondria, Multiple Sclerosis, Myelination, Oxidative Stress, Regeneration, Rehabilitation, Spinal Cord, Synaptic Plasticity
Non-invasive Brain Sodium Quantification in Multiple Sclerosis
It has been suggested that the accumulation of intra-axonal sodium represents a key factor in the degenerative process of MS. Changes in  tissue sodium concentration can be measured in vivo by single quantum Sodium MR Imaging. The application of triple quantum sodium filtration, allows the measurement of intracellular sodium concentration. Using ultra-high field MRI (7T) in collaboration with the Center for Biomedical Imaging at NYU we are investigating whether sodium-related brain tissue damage is critical for the accumulation of clinical disability in MS

MD, University of Genoa

Residency, University of Genoa

Fellowship, Neuroimaging Research Unit, San Raffaele Hospital

Fellowship, New York University, Radiology and Neurology Department

PhD, University of Genoa

436
Publications

Selected Publications

Staying afloat with OCEAN traits: The five-factor model of personality and psychological resilience in multiple sclerosis. Claire E. Wigley, Jonadab dos Santos Silva, Nicole Graziano, Claire Riley, Jonathan Howard, Matilde Inglese, Fred D. Lublin, Melissa Milanak, Sylvia Klineova. Multiple Sclerosis and Related Disorders

Web-based family-reported outcomes to assess family functioning in multiple sclerosis: an Italian multicenter digital survey. Luigi Lavorgna, Giuseppina Miele, Marta Ponzano, Elisabetta Maida, Gianmarco Abbadessa, Floriana Bile, Girolama Alessandra Marfia, Doriana Landi, Francesca Proietti, Matilde Inglese, Alice Laroni, Ilaria Poirè, Giuseppe Romano, Elisabetta Signoriello, Giacomo Lus, Eleonora Ruocco, Francesca Lauro, Laura Rosa, Roberta Lanzillo, Virginia Perutelli, Maria Laura Di Tella, Lidia Mislin Streito, Maria Pia Sormani, Simona Bonavita, Lorys Castelli, Marinella Clerico. International Journal of Medical Informatics

Functional and effective connectivity disruptions of the dopaminergic reward circuit in multiple sclerosis patients with depression. Giada Lombardi, Elisa Leveraro, Emilio Cipriano, Tommaso Sirito, Maria Cellerino, Lorenza Nasone, Gianluca Serafini, Lucio Ghio, Andrea Escelsior, Matilde Inglese. Journal of Neurology, Neurosurgery and Psychiatry

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212-824-9310

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Inglese during 2025 and/or 2026. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Outside Employment

  • University of Genoa

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.