Lisa M Satlin, MD
img_Lisa M Satlin
PROFESSOR | Medicine, Nephrology
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Pediatric Nephrology and Hypertension, Pediatrics
Research Topics
Biomechanics/Bioengineering, Cell Biology, Cellular Differentiation, Cytoskeleton, Developmental Biology, Electrophysiology, Epithelial Cells, Gene Expressions, Growth, Growth Factors and Receptors, Hormones, Imaging, Kidney, Knockout Mice, Membrane Proteins/Channels, Membranes, Phosphorylation, Protein Complexes, Protein Kinases, Protein Phosphatases, Protein Trafficking & Sorting, Signal Transduction, Trafficking, Transporters, Two-Photon Imaging
Multi-Disciplinary Training Area
Disease Mechanisms and Therapeutics (DMT)
The focus of the Satlin lab is on defining the mechanisms leading to the acquisition, maintenance and regulation of transepithelial transport in the mammalian cortical collecting duct, a nephron segment responsible in the adult for the final renal regulation of total body K+ and Na+ homeostasis. Specifically, her lab continues to expand on two major discoveries: (1) unique developmental programs underlying the postnatal expression of ion channels responsible for Na absorption (ENaC) and K secretion (SK/ROMK and BK channels) in this epithelium, thus establishing the physiological basis for total body Na and K retention required for somatic growth and maintenance of blood pressure, and (2) the role of variations in urinary flow rate (i.e., hydrodynamic forces) in mechanoregulation of renal epithelial ion channels in health and disease. Recent efforts have been devoted to developing model systems, including 3D bioprinted collecting ducts and human PSC-derived kidney organoids, which recapitulate ion transport and signaling phenotypes of the in vivo distal nephron. As the lab serves as a national "single nephron physiology" Core of an NIH-funded O'Brien Center for Kidney Research, the techniques available to lab members and external investigators include in vitro microperfusion of single nephron segments, fluorescent functional imaging of single cells in native tissue (for measurement of cell pH, calcium, K+ and Na+), patch clamp studies of single cells for analysis of channel activity, and molecular techniques (real time PCR, immunoblotting) applied to single cells and tubules.

MD, Columbia University College of Physicians & Surgeons

Residency, Pediatrics, Columbia Presbyterian Medical Center

Fellowship, Nephrology, Albert Einstein College of Medicine-Yeshiva University


Pediatric Nephrology
American Board of Pediatrics


Selected to deliver the 2018 Carl W. Gottschalk Distinguished Lectureship of the APS Renal Section


Jacobi Medallion Recipient

Mount Sinai


Recipient of the Barry M. Brenner Endowed Lectureship from the American Society of Nephrology


Selected as the Hans Ussing Lecturer, American Physiological Society, Annual Meeting of the Federation of American Societies for Experimental Biology

American Physiological Society


Recipient of the J. Lester Gabrilove Award

Mount Sinai


KUFA National Medal Award in Pediatric Nephrology

The Kidney & Urology Foundation of America

Commitment to Children: Meet Lisa M. Satlin, MD

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Satlin during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.


  • Washington University, St. Louis

Industry-Sponsored Lectures: MSSM faculty occasionally give lectures at events sponsored by industry, but only if the events are free of any marketing purpose

  • Georgetown University

Scientific Advisory Board:

  • Mount Sinai Children's Center Foundation (CCF)
  • American Physician Scientist Association

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.