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Kevin Costa, PhD
img_Kevin Costa
ASSOCIATE PROFESSOR | Medicine, Cardiology
212-241-7122
email
Research Topics
Biomechanics/Bioengineering, Cardiovascular, Cellular Differentiation, Computer Simulation, Cytoskeleton, Mathematical Modeling of Biomedical Systems, Muscle Cells, Regeneration, Stem Cells, Tissue Engineering, Wound Healing
Multi-Disciplinary Training Area
Artificial Intelligence and Emerging Technologies in Medicine [AIET], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT)
Atomic Force Microscopy And Cell Mechanobiology
This research is focused on enhancing and expanding the kinds of measurements that can be obtained from AFM mechanical testing experiments, to better understand how physical forces impact cardiovascular cell function.
Tissue Engineering And Cardiac Repair
This research involves development of innovative new tools and approaches combining soft lithography, cell patterning, and bioreactor design for tissue and organoid engineering, with the overall objective of improving the understanding and efficacy of novel cell- and gene-therapy based approaches for cardiac repair.

MS, Boston University

PhD, University of California, San Diego

143
Publications

Selected Publications

Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2. Chrystian Junqueira Alves, Theodore Hannah, Sita Sadia, Christy Kolsteeg, Angela Dixon, Robert J. Wiener, Ha Nguyen, Murray J. Tipping, Júlia Silva Ladeira, Paula Fernandes da Costa Franklin, Nathália de Paula Dutra de Nigro, Rodrigo Alves Dias, Priscila V. Zabala Capriles, José P. Rodrigues Furtado de Mendonça, Paul A. Slesinger, Kevin D. Costa, Hongyan Zou, Roland H. Friedel. Nature Communications

Enhanced drug classification using machine learning with multiplexed cardiac contractility assays. Reza Aghavali, Erin G. Roberts, Yosuke K. Kurokawa, Erica Mak, Martin Y.C. Chan, Andy O.T. Wong, Ronald A. Li, Kevin D. Costa. Pharmacological Research

Regenerative potential of mouse neonatal intervertebral disc depends on collagen crosslink density. Danielle N. D'Erminio, Kaya A. Adelzadeh, Ashley M. Rosenberg, Robert J. Wiener, Olivia M. Torre, Emily D. Ferreri, Philip Nasser, Kevin D. Costa, Woojin M. Han, Alice H. Huang, James C. Iatridis. iScience

View All Publications

Creating Heart Stem Cells

Atran Berg Laboratory Building Floor 3 Room 39

1428 Madison Ave

New York, NY 10029

212-241-7122

Hess CSM Building Floor 7 Room 105

1470 Madison Ave

New York, NY 10029

Hess CSM Building Floor 7 Room 201

1470 Madison Ave

New York, NY 10029

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Costa during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Board Service

  • Novoheart US Corp

Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)

  • Medera Biopharmaceutical

Founder/Co-Founder/Partner

  • Novoheart International Ltd

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.