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Kevin Costa, PhD
img_Kevin Costa
ASSOCIATE PROFESSOR | Medicine, Cardiology
212-241-7122
email
Research Topics
Biomechanics/Bioengineering, Cardiovascular, Cellular Differentiation, Computer Simulation, Cytoskeleton, Mathematical Modeling of Biomedical Systems, Muscle Cells, Regeneration, Stem Cells, Tissue Engineering, Wound Healing
Multi-Disciplinary Training Area
Artificial Intelligence and Emerging Technologies in Medicine [AIET], Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT)
Atomic Force Microscopy And Cell Mechanobiology
This research is focused on enhancing and expanding the kinds of measurements that can be obtained from AFM mechanical testing experiments, to better understand how physical forces impact cardiovascular cell function.
Tissue Engineering And Cardiac Repair
This research involves development of innovative new tools and approaches combining soft lithography, cell patterning, and bioreactor design for tissue and organoid engineering, with the overall objective of improving the understanding and efficacy of novel cell- and gene-therapy based approaches for cardiac repair.

MS, Boston University

PhD, University of California, San Diego

136
Publications

Selected Publications

Designing a Bioreactor to Improve Data Acquisition and Model the Throughput of Engineered Cardiac Tissues. Camille C. van Neste, Karlo A. Wiley, Serena W. Chang, Joseph Borrello, Irene C. Turnbull, Kevin D. Costa. Journal of Visualized Experiments

Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues. Shangli Cheng, David Brenière-Letuffe, Virpi Ahola, Andy O.T. Wong, Hoi Yee Keung, Bimal Gurung, Zongli Zheng, Kevin D. Costa, Deborah K. Lieu, Wendy Keung, Ronald A. Li. iScience

Rianú: Multi-tissue tracking software for increased throughput of engineered cardiac tissue screening. Jack F. Murphy, Kevin D. Costa, Irene C. Turnbull. Computer Methods and Programs in Biomedicine Update

View All Publications

Creating Heart Stem Cells

Atran Berg Laboratory Building Floor 3 Room 39

1428 Madison Ave

New York, NY 10029

212-241-7122

Hess CSM Building Floor 7 Room 105

1470 Madison Ave

New York, NY 10029

Hess CSM Building Floor 7 Room 201

1470 Madison Ave

New York, NY 10029

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Costa during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Company Founder:

  • NovoHeart, LTD

Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)

  • Medera Biopharmaceutical

Other activities: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Novoheart US Corp

Royalty Payments:

  • Novoheart, Ltd.

Service on Board of Directors: Service in a fiduciary capacity, such as an officer or director, for the following companies:

  • NovoHeart, LTD

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.