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John E Levine, MD
img_John E Levine
PROFESSOR | Medicine, Hematology and Medical Oncology
PROFESSOR | Pediatrics
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Specialties
Pediatrics, Pediatric Hematology-Oncology
Research Topics
Translational Research, Transplantation
Immunosuppression, T Cells, Transplantation
My research focuses on clinical bone marrow transplantation. My primary research focus concentrates on clinical and translational studies for the diagnosis, prevention, and treatment of acute graft-versus-host disease (GVHD). In collaboration with the laboratory of James Ferrara, we developed and validated a GVHD plasma biomarker based scoring system that assigns patients to GVHD risk strata and can be used to determine treatment intensity.

MD, Eastern Virginia Medical School

Residency, Pediatrics, Children's Hospital of Los Angeles

Residency, Pediatrics, Children's Hospital-Los Angeles

Fellowship, Pediatric Hematology-Oncology, Memorial Sloan-Kettering Cancer Center

Fellowship, Pediatric Hematology-Oncology, Memorial Sloan-Kettering Cancer Center

Fellowship, Pediatric Blood & Marrow Transplant, Memorial Sloan-Kettering Cancer Center

Certifications

American Board of Pediatrics

2013

Chair, Pediatric Scientific Interest Group, ASBMT Annual Meeting

2012

Chair, Scientific Program, ASBMT Annual Meeting

2007

Best Doctors in America

2005

Ford Motor Company Leadership in Health Award

198
Publications

Selected Publications

Differences in Acute Graft-Versus-Host Disease (GVHD) Severity and Its Outcomes Between Black and White Patients. Carlos A.Ortega Rios, Muna Qayed, Aaron M. Etra, Ran Reshef, Richard Newcomb, Nicholas Yuhasz, Elizabeth O. Hexner, Paibel Aguayo-Hiraldo, Pietro Merli, William J. Hogan, Daniela Weber, Carrie L. Kitko, Francis Ayuk, Matthias Eder, Stephan A. Grupp, Sabrina Kraus, Karam Sandhu, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, Ioannis Evangelos Louloudis, George Morales, Nikolaos Spyrou, Rachel Young, Ryotaro Nakamura, John E. Levine, James L.M. Ferrara, Yu Akahoshi. Transplantation and Cellular Therapy

Verification of the Prediction Accuracy of a Biomarker-Based Prognostic for Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) After Hematopoietic Cell Transplantation (HCT). Santosh Putta, Bradford Young, Polly Pine, Ju Shi, Vian Amber, Wael Saber, John E. Levine, Stephan A. Grupp. Transplantation and Cellular Therapy

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD. Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis Ayuk, Chantiya Chanswangphuwana, Hannah K. Choe, Matthias Eder, Aaron M. Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Monzr M. Al Malki, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi Bin Chen, Ryotaro Nakamura, John E. Levine, James L.M. Ferrara. Blood

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Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Levine during 2023 and/or 2024. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Calliditas Therapeutics AB
  • Kamada
  • Inhibrx
  • MaaT Pharma
  • Medexus
  • Bluebird Bio
  • Mesoblast Ltd.
  • Editas
  • VectivBio AG
  • X4 Pharmaceuticals
  • Forte Biosciences
  • Symbio

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.