John E Levine - Pediatrics | Mount Sinai

Biography

Specialties

Pediatrics, Pediatric Hematology-Oncology

Research Topics

Translational Research, Transplantation

Research

Immunosuppression, T Cells, Transplantation

My research focuses on clinical bone marrow transplantation. My primary research focus concentrates on clinical and translational studies for the diagnosis, prevention, and treatment of acute graft-versus-host disease (GVHD). In collaboration with the laboratory of James Ferrara, we developed and validated a GVHD plasma biomarker based scoring system that assigns patients to GVHD risk strata and can be used to determine treatment intensity.

Education

MD, Eastern Virginia Medical School

Residency, Pediatrics, Children's Hospital of Los Angeles

Residency, Pediatrics, Children's Hospital-Los Angeles

Fellowship, Pediatric Hematology-Oncology, Memorial Sloan-Kettering Cancer Center

Fellowship, Pediatric Blood & Marrow Transplant, Memorial Sloan-Kettering Cancer Center

Certifications

American Board of Pediatrics

Honors & Awards

2013

Chair, Pediatric Scientific Interest Group, ASBMT Annual Meeting

2012

Chair, Scientific Program, ASBMT Annual Meeting

2007

Best Doctors in America

2005

Ford Motor Company Leadership in Health Award

Publications

202

Publications

Selected Publications

Serial Clinical and Biomarker Monitoring during Graft-Versus-Host Disease Treatment Identifies Distinct Risk Strata Including an Ultra-Low Risk Group. Nikolaos Katsivelos, Nikolaos Spyrou, Daniela Weber, Ingrid Vasova, Francis Ayuk, Hannah Choe, William Hogan, Zachariah DeFilipp, Muna Qayed, Aaron M. Etra, Karam Sandhu, Sabrina Kraus, Tim Olson, Elizabeth Hexner, Paibel Aguayo-Hiraldo, Ran Reshef, Evelyn Ullrich, Tal Schechter, Carrie Kitko, Chantiya Chanswangphuwana, Pietro Merli, Yu Akahoshi, Janna Baez, Gilbert Eng, Rahnuma Beheshti, Steven Kowalyk, George Morales, Ioannis Evangelos Louloudis, Rachel Young, Ernst Holler, Ryotaro Nakamura, James L.M. Ferrara, John E. Levine. Transplantation and Cellular Therapy

1<sub>8</sub> F-FLT PET and Blood-based Biomarkers for Identifying Gastrointestinal Graft versus Host Disease after Allogeneic Cell Transplantation. Jennifer Holter-Chakrabarty, Lacey McNally, John Levine, James Ferrara, Sara K. Vesely, Christopher G. Kanakry, Tabitha Garwe, Zheng Han, Manu Pandey, Joshua Glover, Yuejin Wen, Ron Gress, Kirsten M. Williams. Radiology: Imaging Cancer

Correction to: Anti-CD3/CD7 immunoconjugate (T-Guard) for severe, steroid-refractory GVHD: final report of BMT CTN 2002 (Bone Marrow Transplantation, (2023), 58, 12, (1416-1418), 10.1038/s41409-023-02110-4). Gabrielle Meyers, Mehdi Hamadani, Michael Martens, Haris Ali, Patrice Chevallier, Hannah Choe, Andrew C. Harris, Ernst Holler, Eric van Hooren, Willem Klaassen, Eric Leifer, Ypke van Oosterhout, Lia Perez, Iskra Pusic, Matthias Stelljes, Walter van der Velden, Emanuele Ammatuna, David Beauvais, Jérôme Cornillon, Richard T. Maziarz, Johannes Schetelig, Jennifer Romeril, Margaret L. MacMillan, John E. Levine, Gérard Socié. Bone Marrow Transplantation

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Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Levine during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

Calliditas Therapeutics AB
Glaxosmithkline
Mesoblast Inc
Equillium, Inc. HQ
Incyte Corporation
Medexus
Kitch Attorneys and Counselors
VectivBio AG
Forte Biosciences
Symbio

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Levine during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

Calliditas Therapeutics AB
Glaxosmithkline
Mesoblast Inc
Equillium, Inc. HQ
Incyte Corporation
Medexus
Kitch Attorneys and Counselors
VectivBio AG
Forte Biosciences
Symbio

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.