Jean-Frederic Colombel, MD
img_Jean-Frederic Colombel
PROFESSOR | Medicine, Gastroenterology
PROFESSOR | Immunology & Immunotherapy
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Specialties
Gastroenterology

MD, University of Cincinnati College of Medicine

Fellowship, Transplant Hepatology, Hospital Center University De Lille

Certifications

American Board of Internal Medicine
Publications

Selected Publications

Long-term efficacy and safety of upadacitinib in patients with moderately to severely active ulcerative colitis: an interim analysis of the phase 3 U-ACTIVATE long-term extension study. Remo Panaccione, Séverine Vermeire, Silvio Danese, Peter D.R. Higgins, Gary R. Lichtenstein, Hiroshi Nakase, Sarah Glover, Jean Frédéric Colombel, Jason Eccleston, Michelle Kujawski, Valencia Remple, Xuan Yao, Ziqian Geng, Hannah Palac, Dolly Sharma, Smitha Suravaram, Stefan Schreiber. The Lancet Gastroenterology and Hepatology

Efficacy and Safety of Upadacitinib for Perianal Fistulizing Crohn's Disease: A Post Hoc Analysis of 3 Phase 3 Trials. Jean Frédéric Colombel, Ana P. Lacerda, Peter M. Irving, Remo Panaccione, Walter Reinisch, Florian Rieder, Adam Steinlauf, David Schwartz, Tian Feng, Elena Dubcenco, Samuel I. Anyanwu, F. Stephen Laroux, Colla Cunneen, Nick Powell. Clinical Gastroenterology and Hepatology

Perianal Fistulizing Crohn's Disease: Utilizing the TOpClass Classification in Clinical Practice to Provide Targeted Individualized Care. Luke N. Hanna, Sulak Anandabaskaran, Nusrat Iqbal, Jeroen Geldof, Jean Frédéric LeBlanc, Anders Dige, Lilli Lundby, Séverine Vermeire, André D'Hoore, Bram Verstockt, Gabriele Bislenghi, Danny De Looze, Triana Lobaton, Dirk Van de Putte, Antonino Spinelli, Michele Carvello, Silvio Danese, Christianne J. Buskens, Krisztina Gecse, Roel Hompes, Marte Becker, Jarmila van der Bilt, Willem Bemelman, Shaji Sebastian, Gordan Moran, Amy L. Lightner, Serre Yu Wong, Jean Frédéric Colombel, Benjamin L. Cohen, Stefan D. Holubar, Nik S. Ding, Corina Behrenbruch, Kapil Sahnan, Ravi Misra, Phillip Lung, Ailsa Hart, Phil Tozer. Clinical Gastroenterology and Hepatology

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Looking Back and in the Distance: Are We on Track to Change IBD Patients' Lives

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Colombel during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Protagonist Therapeutics, Inc.
  • Envision Pharma
  • Immunic
  • GlaxoSmithKline
  • Pfizer Inc.
  • Shire
  • Ferring Pharmaceuticals
  • Boehringer Ingelheim Corporation
  • Anapty Bio
  • Boxer
  • Eli Lilly and Company
  • Ensho
  • Merck & Co., Inc.
  • Microbia Novartic
  • Landos
  • Alimentiv
  • Tigenix
  • Celgene Corporation
  • Teva
  • Amgen Inc.
  • Sanofi
  • Takeda Pharmaceuticals International GmbH
  • Otsuka Pharmaceutical Co., Ltd.
  • Bristol-Myers Squibb
  • WEBMD Health Corp
  • Integritas Communication
  • Prometheus Laboratories Inc.
  • AbbVie Inc.
  • Sun
  • Arena
  • Imedex, LLC.
  • Seres
  • Allergan, Inc.
  • Genentech, Inc.
  • Janssen Pharmaceuticals, Inc.
  • Union Therapeutics A/S
  • Iterative Scope
  • Vifor
  • Galmed research
  • Guide Point
  • Kaleido

Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)

  • Intestinal Biotech Development

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.