Jaymin Kathiriya, PhD
img_Jaymin Kathiriya
ASSISTANT PROFESSOR | Medicine, Pulmonary, Critical Care and Sleep Medicine
ASSISTANT PROFESSOR | Cell, Developmental & Regenerative Biology
Research Topics
Cellular Differentiation, Computational Biology, Developmental Biology, Epigenetics, Epithelial Cells, Gene Expressions, Gene Regulation, Gene editing, Genetics, Genomics, Lung, Organogenesis, Regeneration, Respiratory, Stem Cells, Transcription Factors, Transgenic Mice
Multi-Disciplinary Training Area
Development Regeneration and Stem Cells [DRS]
New topic
The Kathiriya Lab focuses on studying how fate decisions of distal lung epithelial stem cells are affected by intrinsic and extrinsic factors. Upon injury, dedicated adult stem/progenitor cells are preferentially activated to locally regenerate injured regions of the distal lung. Subsequently, the microenvironment and surrounding cell types influence cytoskeletal remodeling of differentiating stem cells, often causing maladaptive differentiation during disease progression. The Kathiriya lab aims to investigate what makes the stem cells respond preferentially upon injury and the mechanisms affecting the cytoskeletal remodeling of distal lung epithelial stem cells to cause abnormal regeneration, resulting in disease state. The overall aim of the lab is to create therapeutic interventions that can help stem cells regenerate functional alveoli. To achieve this goal, the Kathiriya Lab integrates in vitro 3D stem cell organoids, in vivo mouse genetics, and in silico computational data modeling.

BS, University of California, Davis

MS, University of California, Irvine

PhD, University of South Florida

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Dr. Kathiriya has not yet completed reporting of Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.