Isabelle M Germano, MD, MBA
img_Isabelle M Germano
PROFESSOR | Neurosurgery
PROFESSOR | Oncological Sciences
PROFESSOR | Neurology
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Neurosurgery, Cancer (Oncology)
Research Topics
Anti-Tumor Therapy, Apoptosis/Cell Death, Autophagy, Brain, Cancer, Cellular Differentiation, Gene Expressions, Gene Therapy, Metastasis, Migration, Molecular Biology, Neuroscience, Seizure, Stem Cells, Translation, Tumor Suppressor Genes, Tumorigenesis
Translational research for malignant brain tumors
The main focus of the laboratory is to investigate new strategies for adjuvant treatment of malignant brain tumors. With the support from the National Institutes of Health, NIH, private foundations and Industry, the laboratory has been very productive in investigating new promising modalities and compound to kill brain tumor cells. Embryonic stem cells are currently used in animal models to transfer genes to brain tumors.

Image-guide computer-assisted neurosurgery
One of the pioneers in this field, Dr. Germano continues to collaborate with the industry in making neurosurgical resections more accurate and less invasive.

Related Link:
Brain Tumor and Gene Therapy Laboratory

MD, University of Turin

Residency, Surgery (General Surgery), University of California at San Francisco School of Medicine

Residency, Neurosurgery, University of California at San Francisco School of Medicine

Residency, Neurosurgery, Albert Einstein College of Medicine-Yeshiva University

Fellowship, Neurosurgery, University of Zurich

Fellowship, Neurosurgery, Montreal Neurological Institute


American Board of Neurological Surgery


Charles A. Elsberg, MD Lecturer

The New York Society for Neurosurgery


Cullman Family Award for Excellence in Physician Communication

Mount Sinai Health System


Most Compassionate Top 10 Doctors



Leksell Radiosurgery Award

American Association of Neurological Surgeons


Leksell Radiosurgery Award

American Association of Neurological Surgeons


Technology Development Award

Icahn School of Medicine at Mount Sinai


Neurological Devices Voting Member

Food and Drug Administration


Research grant: Brain tumors and gene transfer

National Institute of Health


Brain Tumor Research

Goldhirsh Foundation


Life Time Member

Who is Who Strathmore's


New York State Certificats of Recognition, Dedication and Service to the Italians Culture and Community

New York State


Certificate of Excellence in Youth Education

New York City Department of Education and Mount Sinai School of Medicine


Neurosurgery Research Award

New York State Society


America's Top Cancer Doctors

Castle Connolly


Best Doctors Of New York

New York Magazine


Top Doctors New York Metro Area

Castle Connolly


Mary Putnam Jacobi Award

Women's Medical Association of New York City


W. Penfield Award

American Epilepsy Society

WFNS YNF Webinar - Dr. Isabelle Germano on Brain Tumors
Isabella Germano, MD at AANS 2018
Malignant Brain Tumors
Medical Student Lecture Series: Radiosurgery and Stereotaxy with Isabelle M. Germano, MD, MBA
Isabelle Germano, MD, MBA, FACS
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Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Germano during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.


  • Neosoma
  • brainlab

Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)

  • Elminda

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.