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Evren U Azeloglu, PhD
img_Evren U Azeloglu
ASSOCIATE PROFESSOR | Medicine, Nephrology
ASSOCIATE PROFESSOR | Pharmacological Sciences
212-241-8519
email
Research Topics
Biomechanics/Bioengineering, Biophysics, Cardiovascular, Computational Biology, Cytoskeleton, Kidney, Mathematical Modeling of Biomedical Systems, Mathematical and Computational Biology, Nanotechnology, Signal Transduction, Systems Biology, Tissue Engineering
Our main goal at the Systems Bioengineering Lab is to understand mechanobiological decision-making capabilities and to develop novel therapeutics for precision medicine. We employ multiscale experimental and computational techniques as well as microfabrication and tissue engineering methods to study cell signaling, biomechanics, tissue function and regeneration using human induced pluripotent stem cell-derived cardiovascular and renal model systems. We also use multi-platform omics technologies and network analyses for identification of key information processing hubs and regulatory motifs that can be used as therapeutic targets in drug development for complex diseases such as hypertension, diabetic nephropathy and heart failure. See Azeloglu Lab website for more details.

BE, Stony Brook University

MS, Stony Brook University

PhD, Columbia University

2015

NephCure Kidney International ASN Foundation Kidney Research Award

American Society of Nephrology

2010

Howard Hughes Medical Institute Fellowship

Life Science Research Foundation

2008

Yuen-huo Hung & Chao-chin Huang Award (2009)

Columbia University

2005

Stony Wold Herbert Fellowship

79
Publications

Selected Publications

HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Man Chen, Madhav C. Menon, Wenlin Wang, Jia Fu, Zhengzi Yi, Zeguo Sun, Jessica Liu, Zhengzhe Li, Lingyun Mou, Khadija Banu, Sui Wan Lee, Ying Dai, Nanditha Anandakrishnan, Evren U. Azeloglu, Kyung Lee, Weijia Zhang, Bhaskar Das, John Cijiang He, Chengguo Wei. Nature Communications

Computational study of biomechanical drivers of renal cystogenesis. Gerard A. Ateshian, Katherine A. Spack, James C. Hone, Evren U. Azeloglu, G. Luca Gusella. Biomechanics and Modeling in Mechanobiology

An atlas of healthy and injured cell states and niches in the human kidney. Blue B. Lake, Rajasree Menon, Seth Winfree, Qiwen Hu, Ricardo Melo Ferreira, Kian Kalhor, Daria Barwinska, Edgar A. Otto, Michael Ferkowicz, Dinh Diep, Nongluk Plongthongkum, Amanda Knoten, Sarah Urata, Laura H. Mariani, Abhijit S. Naik, Sean Eddy, Bo Zhang, Yan Wu, Diane Salamon, James C. Williams, Xin Wang, Karol S. Balderrama, Paul J. Hoover, Evan Murray, Jamie L. Marshall, Teia Noel, Anitha Vijayan, Austin Hartman, Fei Chen, Sushrut S. Waikar, Sylvia E. Rosas, Francis P. Wilson, Paul M. Palevsky, Krzysztof Kiryluk, John R. Sedor, Robert D. Toto, Chirag R. Parikh, Eric H. Kim, Rahul Satija, Anna Greka, Evan Z. Macosko, Peter V. Kharchenko, Joseph P. Gaut, Jeffrey B. Hodgin, Richard Knight, Stewart H. Lecker, Isaac Stillman, Evren U. Azeloglu, Ravi Iyengar, Jens Hansen. Nature

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Annenberg Building Floor 23 Room 02D

1468 Madison Ave

New York, NY 10029

212-241-8519

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Azeloglu during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Other activities: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Access for Life
  • RenalytixAI

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.