Daniel Puleston, PhD
img_Daniel Puleston
ASSISTANT PROFESSOR | Oncological Sciences
Research Topics
Cancer, Cell Biology, Cellular Differentiation, Cellular Immunity, Immunology, Inflammation, Lymphocytes, Macrophage, Metabolism, Metabolomics, T Cells
Multi-Disciplinary Training Area
Cancer Biology [CAB]
The lab’s goal is to understand how immunity is fueled. In the Puleston Lab, we believe that by turning our attention to cellular metabolism, we can decode key underlying principles of immune cell biology. Most importantly, by investigating the intersection of metabolism, pathology, and the immune system, we strive to expose novel metabolic vulnerabilities that can be utilized for disease prevention and therapy. Major areas of investigation include: - How perturbations in cellular metabolism drive tumorigenesis - How local metabolic factors instruct the acquisition of tissue-specific signatures - Metabolic pathways governing immune cell dysfunction in tumors - Metabolic regulation of pluri- and multipotency in stem and progenitor cells

PhD, University of Oxford

Johns Hopkins University

Max Planck Institute of Immunobiology & Epigenetics

University of Oxford

Sir Henry Wellcome Fellowship

The Wellcome Trust

EMBO Long-Term Fellowship


EPA Cephalosporin Junior Research Fellowship

Linacre College, Oxford

Prize Ph.D in Medicine, University of Oxford

University of Oxford

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Puleston did not report having any of the following types of financial relationships with industry during 2022 and/or 2023: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.