We study the contribution of inflammatory cells infiltrating the atherosclerotic arterial wall to the progression of the disease:  identification of the cellular and molecular immune interactions that occur in the atherosclerotic plaque

We investigate the contribution of circulating monocyte subsets as a source of a new isoform of tissue factor with angiogenic activity to the growth of intimal neovessel in atherosclerosis as a potential mechanism of lesion instability culminating in the onset of ischemic cardiovascular events (i.e. stroke and myocardial infarction).