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Brian Kopell, MD
img_Brian Kopell
PROFESSOR | Neurosurgery
PROFESSOR | Neurology
PROFESSOR | Neuroscience
PROFESSOR | Psychiatry
212-523-8340
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Specialties
Neurosurgery
Electrophysiological Biomarkers to Optimize Deep Brain Stimulation for Depression
The Icahn School of Medicine at Mount Sinai is running a single-center experimental trial of deep brain stimulation (DBS) to the subcallosal cingulate region (Area 25) for treatment resistant depression (TRD). The goal of this study is to refine and optimize this treatment approach using a newly available neuromodulation system (the Medtronic Summit RC+S) that allows brain activity during ongoing therapeutic DBS to be recorded from the brain in real-time. This study will further define brain readouts that track depression recovery, providing novel strategies to monitor and guide treatment and device programming decisions in patients receiving DBS for TRD.
   
Participating Mount Sinai Programs:
To enroll in the study contact Emma Meyer at 212-241-6539 or dac@mssm.edu.
For more information visit Mount Sinai Clinical Trials.


Cortical Stimulation for Tinnitus
Cortical and Deep Brain Stimulation for Depression and Obsessive Compulsive Disorder
Intraoperative Image-Guidance for Deep Brain Stimulation

MD, New York University School of Medicine

Internship, Surgery (General Surgery), NYU Medical Center

Residency, Neurosurgery, NYU Medical Center

Fellowship, Neurosurgery, Cleveland Clinic Foundation

Certifications

American Board of Neurological Surgery

2015-2019

Top Doctors - New York Metro Area

Castle Connolly

106
Publications

Selected Publications

Correction to: Divergent landscapes of A-to-I editing in postmortem and living human brain (Nature Communications, (2024), 15, 1, (5366), 10.1038/s41467-024-49268-z). Miguel Rodriguez de los Santos, Brian H. Kopell, Ariela Buxbaum Grice, Gauri Ganesh, Andy Yang, Pardis Amini, Lora E. Liharska, Eric Vornholt, John F. Fullard, Pengfei Dong, Eric Park, Sarah Zipkowitz, Deepak A. Kaji, Ryan C. Thompson, Donjing Liu, You Jeong Park, Esther Cheng, Kimia Ziafat, Emily Moya, Brian Fennessy, Lillian Wilkins, Hannah Silk, Lisa M. Linares, Brendan Sullivan, Vanessa Cohen, Prashant Kota, Claudia Feng, Jessica S. Johnson, Marysia Kolbe Rieder, Joseph Scarpa, Girish N. Nadkarni, Minghui Wang, Bin Zhang, Pamela Sklar, Noam D. Beckmann, Eric E. Schadt, Panos Roussos, Alexander W. Charney, Michael S. Breen. Nature Communications

Divergent landscapes of A-to-I editing in postmortem and living human brain. Miguel Rodriguez de los Santos, Brian H. Kopell, Ariela Buxbaum Grice, Gauri Ganesh, Andy Yang, Pardis Amini, Lora E. Liharska, Eric Vornholt, John F. Fullard, Pengfei Dong, Eric Park, Sarah Zipkowitz, Deepak A. Kaji, Ryan C. Thompson, Donjing Liu, You Jeong Park, Esther Cheng, Kimia Ziafat, Emily Moya, Brian Fennessy, Lillian Wilkins, Hannah Silk, Lisa M. Linares, Brendan Sullivan, Vanessa Cohen, Prashant Kota, Claudia Feng, Jessica S. Johnson, Marysia Kolbe Rieder, Joseph Scarpa, Girish N. Nadkarni, Minghui Wang, Bin Zhang, Pamela Sklar, Noam D. Beckmann, Eric E. Schadt, Panos Roussos, Alexander W. Charney, Michael S. Breen. Nature Communications

Deep Brain Stimulation for Obsessive-Compulsive Disorder: Optimal Stimulation Sites. Garance M. Meyer, Barbara Hollunder, Ningfei Li, Konstantin Butenko, Till A. Dembek, Lauren Hart, Cristina Nombela, Philip Mosley, Harith Akram, Nicola Acevedo, Benjamin M. Borron, Tina Chou, Juan Pablo Castaño Montoya, Bryan Strange, Juan A. Barcia, Himanshu Tyagi, David J. Castle, Andrew H. Smith, Ki Sueng Choi, Brian H. Kopell, Helen S. Mayberg, Sameer A. Sheth, Wayne K. Goodman, Albert F.G. Leentjens, R. Mark Richardson, Susan L. Rossell, Peter Bosanac, G. Rees Cosgrove, Jens Kuhn, Veerle Visser-Vandewalle, Martijn Figee, Darin D. Dougherty, Shan H. Siddiqi, Ludvic Zrinzo, Eileen Joyce, Juan Carlos Baldermann, Michael D. Fox, Clemens Neudorfer, Andreas Horn. Biological Psychiatry

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To Dream Again
Deep Brain Stimulation Surgery to treat Parkinson's Disease at Mount Sinai Hospital

Mount Sinai West

1000 Tenth Avenue, Tenth Floor

New York, NY 10019

212-523-8340

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Kopell during 2023 and/or 2024. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Abbott Neuromodulation
  • Turing Medical
  • Medtronic, Inc

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.