Brian Kopell, MD
img_Brian Kopell
PROFESSOR | Neurosurgery
PROFESSOR | Neuroscience
PROFESSOR | Neurology
PROFESSOR | Psychiatry
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Electrophysiological Biomarkers to Optimize Deep Brain Stimulation for Depression
The Icahn School of Medicine at Mount Sinai is running a single-center experimental trial of deep brain stimulation (DBS) to the subcallosal cingulate region (Area 25) for treatment resistant depression (TRD). The goal of this study is to refine and optimize this treatment approach using a newly available neuromodulation system (the Medtronic Summit RC+S) that allows brain activity during ongoing therapeutic DBS to be recorded from the brain in real-time. This study will further define brain readouts that track depression recovery, providing novel strategies to monitor and guide treatment and device programming decisions in patients receiving DBS for TRD.
Participating Mount Sinai Programs:
To enroll in the study contact Emma Meyer at 212-241-6539 or
For more information visit Mount Sinai Clinical Trials.

Cortical Stimulation for Tinnitus
Cortical and Deep Brain Stimulation for Depression and Obsessive Compulsive Disorder
Intraoperative Image-Guidance for Deep Brain Stimulation

MD, New York University School of Medicine

Internship, Surgery (General Surgery), NYU Medical Center

Residency, Neurosurgery, NYU Medical Center

Fellowship, Neurosurgery, Cleveland Clinic Foundation


American Board of Neurological Surgery


Top Doctors - New York Metro Area

Castle Connolly

To Dream Again
Deep Brain Stimulation Surgery to treat Parkinson's Disease at Mount Sinai Hospital

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Kopell during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.


  • Medtronic, Inc.
  • Abbott Neuromodulation
  • ClearPoint Neuro

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.