Basil G Hanss, PhD
img_Basil G Hanss
SENIOR ASSOCIATE DEAN FOR STUDENT AND POSTDOCTORAL AFFAIRS | Graduate School of Biomedical Sciences
ASSOCIATE DEAN FOR GRADUATE SCHOOL WELL-BEING AND RESILIENCE | Graduate School of Biomedical Sciences
ASSOCIATE PROFESSOR | Medicine, Nephrology
ASSOCIATE PROFESSOR | Medical Education
ASSOCIATE PROFESSOR | Pharmacological Sciences
Research Topics
Bioinformatics, Biophysics, Cell Biology, Epithelial Cells, Gene Therapy, Intracellular Transport, Kidney, Membrane Proteins/Channels, Membranes, Molecular Biology, Nanotechnology, Protein Complexes, Protein Structure/Function, Proteomics, Structural Biology, Transporters
Multi-Disciplinary Training Area
Disease Mechanisms and Therapeutics (DMT), Neuroscience [NEU]

Characterization of a nucleic acid transporter

The precise molecular mechanism(s) responsible for nucleic acid transport across the plasma membrane are being defined. This research has led to the identification and partial characterization of a plasma membrane protein complex that functions as a highly selective nucleic acid-conducting channel. To date the substrate specificity of the channel has been defined and several channel blockers identified. In addition, three putative channel complex proteins have been cloned. Having now obtained definitive evidence for the role of one of these proteins in channel function future projects focus on definition of the role of the other two proteins. Strategies are being applied to develop a molecular model of nucleic acid transport

BS, Lewis and Clark College

PhD, Tulane University

NIDR/NIH

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Dr. Hanss has not yet completed reporting of Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.