Dr. Ferket's research focuses on applying quantitative methods to identify the best medical decisions for patient populations and the individual patient. He employs mathematical modeling and computer simulation techniques to estimate health and economic outcomes following healthcare interventions, which can be expected for individual risk profiles based on data from clinical trials, population cohort studies, electronic health records and administrative claims databases. He has performed various decision and prognostic modeling studies to evaluate health benefits, risks and economic outcomes for different chronic, non-communicable disease types with the purpose of a) guiding policy makers in decision making at the population level and b) guiding the individual and his/her physician in selecting the optimal medical option(s). His research particularly concerns: 1) prevention of cardiovascular disease, 2) value of surgical procedures, and 3) utility of novel biomarkers and imaging tests.