Anne Schaefer, MD, PhD
img_Anne Schaefer
PROFESSOR | Neuroscience
PROFESSOR | Psychiatry
Research Topics
Basal Ganglia, Brain, Chromatin, Epigenetics, Genetics, Human Genetics and Genetic Disorders, Knockout Mice, Locomotion, Mental Retardation, Multiple Sclerosis
Multi-Disciplinary Training Area
Neuroscience [NEU]
Our research focuses on identifying the epigenetic basis of neurodegenerative and psychiatric disorders. We study how miRNAs and histone modifying enzymes contribute to the establishment and maintenance of neuronal identity and specialized functions. We are particularly interested in understanding the epigenetic mechanisms of cellular plasticity and its role in regulation of microglia-neuron communication in health and disease. One of the major focuses of our research lies in the development of animal models of human neurological disease associated with abnormal function of epigenetic regulators of different types. Using pioneering technologies including cell type specific analysis of mRNAs, miRNAs and chromatin modifications in neurons in vivo, our research aims at understanding the mechanism of neurological disorders and at their potential treatment by targeting the neuronal epigenome.

MD, Johannes Gutenberg University

MD, Charité University

Postdoc, The Rockefeller University


Inaugural NINDS Landis Award for Outstanding Mentorship



Inventor of the Year 2018 Award

Mount Sinai


Harold and Golden Lamport Research Award

Mount Sinai


Technology Development Fund Award

Mount Sinai Innovation


Cure Challenge Award

Cure Challenge


Kavli Frontiers in Science Fellow

The National Academy of Science


Chrissy Rossi Investigator

Chrissy Rossi


Research Award

Seaver Autism Center


NIH Director’s New Innovator Award



NARSAD Young Investigator Award



Research Fellowship

German Research Foundation DFG


Hans-Hench Award 2005

German Society for Immunology, Germany


Summa cum lauden

Charité University Berlin


Research Award

Keystone Scholar Travel Award


USA Research Scholarship

The German National Academic Foundation



German National Merit Foundation

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Schaefer during 2023 and/or 2024. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Board Service

  • Max Planck Institute

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.