Alyssa M Wilson, PhD
img_Alyssa M Wilson
ASSISTANT PROFESSOR | Neurology
ASSISTANT PROFESSOR | Psychiatry
Neurological Function, Gene Product Regulation, and Disease State in Adults Who Experience Neuropsychiatric Disease
Dr. Wilson’s research focuses on building descriptions of the relationships between neurological function, gene product regulation, and disease state in adults who experience neuropsychiatric disease. Neuropsychiatric diseases are complex, and their often-widespread impact on function can make treatment difficult. To get a better understanding of how particular neurological changes may be related to disease symptoms, Dr. Wilson uses artificial intelligence to consider multiple aspects of a patient’s status in combination, including transcriptomic and epigenomic data from various brain regions (which inform about how gene expression is regulated); anatomical data from various brain regions (which can show how cells may change or interact); and clinical data, such as neurological health measures and comorbidity records. By revealing new insights about how genetics, other cell-level changes, environmental factors, and disease progression influence each other in patient populations, this effort aims to ultimately highlight ways to improve therapeutic strategies for these diseases.

2019

Best Poster

Cerebellum Gordon Research Conference

Publications

Selected Publications

Preservation of cellular structure via immersion fixation in brain banking. Macy Garrood, Emma L. Thorn, Adam Goldstein, Allison Sowa, William Janssen, Alyssa Wilson, Claudia S. López, Raakhee Shankar, Erin S. Stempinski, Kurt Farrell, John F. Crary, Andrew T. McKenzie. Free Neuropathology

The single-cell opioid responses in the context of HIV (SCORCH) consortium. Seth A. Ament, Rianne R. Campbell, Mary Kay Lobo, Joseph P. Receveur, Kriti Agrawal, Alejandra Borjabad, Siddappa N. Byrareddy, Linda Chang, Declan Clarke, Prashant Emani, Dana Gabuzda, Kyle J. Gaulton, Michelle Giglio, Federico M. Giorgi, Busra Gok, Chittibabu Guda, Eran Hadas, Brian R. Herb, Wen Hu, Anita Huttner, Mohammad R. Ishmam, Michelle M. Jacobs, Jennifer Kelschenbach, Dong Wook Kim, Cheyu Lee, Shuhui Liu, Xiaokun Liu, Bertha K. Madras, Anup A. Mahurkar, Deborah C. Mash, Eran A. Mukamel, Meng Niu, Richard M. O’Connor, Chelsea M. Pagan, Alina P.S. Pang, Piya Pillai, Vez Repunte-Canonigo, W. Brad Ruzicka, Jay Stanley, Timothy Tickle, Shang Yi A. Tsai, Allen Wang, Lauren Wills, Alyssa M. Wilson, Susan N. Wright, Siwei Xu, Junchen Yang, Maryam Zand, Le Zhang, Jing Zhang, Schahram Akbarian, Shilpa Buch, Christine S. Cheng, Michael J. Corley, Howard S. Fox, Mark Gerstein, Suryaram Gummuluru, Myriam Heiman, Ya Chi Ho, Manolis Kellis, Paul J. Kenny, Yuval Kluger, Teresa A. Milner, David J. Moore, Susan Morgello, Lishomwa C. Ndhlovu, Tariq M. Rana, Pietro Paolo Sanna, John S. Satterlee, Nenad Sestan, Stephen A. Spector, Serena Spudich, Hagen U. Tilgner, David J. Volsky, Owen R. White, Dionne W. Williams, Hongkui Zeng. Molecular Psychiatry

Neuronal accumulation of hyperphosphorylated tau protein predicts stable memory impairment in people living with HIV. Jairo Gonzalez, Alyssa Wilson, Desiree Byrd, Etty P. Cortes, John F. Crary, Susan Morgello. AIDS

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Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Dr. Wilson has not yet completed reporting of Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.