Alexandros D Polydorides, MD, PhD
img_Alexandros D Polydorides
PROFESSOR | Artificial Intelligence and Human Health
PROFESSOR | Pathology, Molecular and Cell Based Medicine
PROFESSOR | Medical Education
PROFESSOR | Medicine, Gastroenterology
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Specialties
Anatomic Pathology and Clinical Pathology
Research Topics
Barrett’s Esophagus, Cancer, Gastroenterology, Metastasis, Pathology

PhD, Rockefeller University

MD, Weill Medical College of Cornell University

Residency, Pathology - Anatomic/Pathology - Clinical, New York Presbyterian Hospital-Weill Cornell Center

Fellowship, Pathology - Gastrointestinal, University of Michigan Hospitals

Publications

Selected Publications

Perianal Fistulizing Crohn's Disease–Associated Anorectal and Fistula Cancers: Systematic Review and Expert Consensus. Serre Yu Wong, Cathy Rowan, Elvira Diaz Brockmans, Cindy C.Y. Law, Elisabeth Giselbrecht, Celina Ang, Sergey Khaitov, David Sachar, Alexandros D. Polydorides, Leon Shin han Winata, Bram Verstockt, Antonino Spinelli, David T. Rubin, Parakkal Deepak, Dermot P.B. McGovern, Benjamin D. McDonald, Phillip Lung, Lilli Lundby, Amy L. Lightner, Stefan D. Holubar, Luke Hanna, Carla Hamarth, Jeroen Geldof, Anders Dige, Benjamin L. Cohen, Michele Carvello, Cristiana Bonifacio, Gabriele Bislenghi, Corina Behrenbruch, David H. Ballard, Emre Altinmakas, Shaji Sebastian, Phil Tozer, Ailsa Hart, Jean Frederic Colombel. Clinical Gastroenterology and Hepatology

Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis. Weili Xu, Natasha B. Golovchenko, Irving U. Martínez-Vargas, Andrew Fong, Prateeksha Rout, Sajan Achi, Edie B. Bucar, Jonathan J. Hsieh, Kaylynn J. Vidmar, Lanjing Zhang, Alexandros D. Polydorides, Immo Prinz, George Kollias, Mark R. Frey, Theresa T. Pizarro, Michael P. Verzi, Karen L. Edelblum. Science immunology

Neoplastic Progression Risk in Females With Barrett's Esophagus: A Systematic Review and Meta-Analysis of Individual Patient Data. Pauline A. Zellenrath, Laurelle van Tilburg, Roos E. Pouw, Rena Yadlapati, Yonne Peters, Michael B. Ujiki, Prashanthi N. Thota, Norihisa Ishimura, Stephen J. Meltzer, Noam Peleg, Won Tak Choi, John V. Reynolds, Alexandros D. Polydorides, Arjun D. Koch, Judith Honing, Manon C.W. Spaander. Clinical Gastroenterology and Hepatology

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Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Polydorides during 2024 and/or 2025. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Agilent
  • Merck & Co., Inc.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.